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AB-Biotics launches a psychobiotic that reduces stress and anxiety
29 October 2019

AB-Biotics and Kaneka Probiotics were active participants at the Probiota Asia congress held in Singapore between October 22nd and 24th, organized by NutraIngredients-Asia. This annual event focuses on the  pharmaceutical and food industry market for probiotics, prebiotics and microbiota. AB-Biotics, together with its main shareholder, Kaneka Probiotics, played a leading role, thanks to the launch of this new product.

This event was especially relevant for AB-Biotics as they presented a key product in its strategy: AB-Mind, a probiotic product made with the DR7 strain of Lactobacillus plantarum, 100% natural in composition, which reduces symptoms of stress and anxiety and improves both cognitive and memory functions, whilst contributing to a mental balance that provides a sense of well-being; this is called the psychobiotic effect.

AB-Mind joins the group of products that act on the gut-brain axis, which establishes biochemical communication between the gastrointestinal tract and the central nervous system. The term intestinal-brain connection (gut-brain axis) is commonly used to talk about the role of the microbiome and how it influences actions which take place within the central nervous system.

The AB-Mind strain has been used in numerous in-vivo clinical trials (animal testing) to provide support for its  effect on brain health. In these preclinical trials, it helped to improve reaction time and memory in animals undergoing a controlled stress test, and also demonstrated a protective effect on the ocular neurodegeneration model.

Apart from in-vivo, pre-clinical data, AB-Mind also has carried out a clinical trial on humans, on a population range which experiences moderate stress. Their results showed a reduction of stress and anxiety compared to the placebo, a reduction of cortisol levels (the stress hormone) and also of proinflammatory markers. Moreover, the molecular analyses carried out on patients’ blood samples confirm that the probiotic acts, at least in part, by modulating the tryptophan and tyrosine metabolic pathways, involved in the synthesis of neurotransmitters and immunoregulatory molecules.

Among the activities organized at Probiota Asia was a presentation on October 23rd  by Professor Min-Tze Liong (School of Industrial Technology, Universiti Sains Malaysia entitled “A probiotic for brain, respiratory and gut health”, which was a highlight. Professor Liong explained how the probiotic strain of AB-Mind, isolated from milk extracted from Malaysian cows, has shown the benefits to immunity as described above, in terms of cognition, respiratory diseases and modulation of intestinal microbiota. In addition, Miquel Ángel Bonachera, co-founder and executive co-director of AB-Biotics participated in the roundtable held that day: “What’s next in Probiotics for mental health”. Bonachera explained how the consumption of probiotics helps to achieve balance in the gut microbiome that can subsequently reduce the symptoms of mental illness.

According to Sergi Audivert, co-founder and executve co-director, AB-Biotics will promote its psychobiotic Lactobacillus plantarum DR7 with the aim of leading the market for products aimed at reducing stress and anxiety based upon clinical evidence.

As well as promoting their portfolio, AB-Biotics a morning yoga session was also organised to endorse a healthy and stress-free lifestyle.